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  • Director of Center
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© Clifton E. Barry III, Ph.D., NIAID, NIH.
Colorized scanning electron micrograph of Mycobacterium tuberculosis

About

With Master 2 in Biology-Computer Science obtained from Paris VII Diderot (“mention Bien”) in 2012, I did my internship in R. Brosch’s unit at the Pasteur Institute where I worked on de novo assembly methods and comparative genomics of new strains of Mycobacterium tuberculosis.

Then, I joined B. Dujon’s unit again at Pasteur Institute for 2 years, where I analyzed copy number variation of chromosomes in evolved S. cerevisiae mutants. Analyzing accurately data from high-throughput sequencing was determinant to decipher chromosomal abnormalities.

Since 2014, I am working as a data scientist/analyst engineer at Bioinformatics and Biostatistics HUB (Head: O. Gascuel). My aim is to process big data sets by building analysis pipelines (decipher sequence features/mutations explaining unexpected fitness, classification of mass spectrometry data, …). Another aspect of my work involves teaching, giving lessons to students of all levels.

Keywords : Genetics, Machine Learning, Teaching, …

Courses

09:00
23
Sep 2019
Course

Introduction à l’analyse Bio-informatique de séquences

L’objectif de cette formation est de présenter, au travers de l’utilisation d’outils largement utilisés, quelques grands principes sur l’analyse de séquence. L’ensemble de la formation combine exposés théoriques (fondements méthodologiques des programmes) et applications […]
Bioinformatics and Biostatistics HUB
Expertise group : SysBio – System Bioinformatics
Expertise group: Genomics
Computational Biology
Corinne Maufrais
Damien Mornico
Varun Khanna
Frédéric Lemoine
2019-09-23 09:00:00 2019-09-27 17:00:00 Europe/Paris Introduction à l’analyse Bio-informatique de séquences L’objectif de cette formation est de présenter, au travers de l’utilisation d’outils largement utilisés, quelques grands principes sur l’analyse de séquence. L’ensemble de la formation combine exposés théoriques (fondements méthodologiques des programmes) et applications […] Institut Pasteur, Rue du Docteur Roux, Paris, France
09:30
19
Mar 2018
Course

Analyse de séquences

OBJECTIFS : Les biologistes sont régulièrement confrontés à des gènes (ou des protéines) de fonctions inconnues ou mal annotés. Dans ce contexte, maîtriser quelques techniques basiques d’analyse de séquences peut se révéler d’une aide […]
Expertise group : SysBio – System Bioinformatics
Bioinformatics and Biostatistics HUB
Expertise group: Genomics
Computational Biology
Corinne Maufrais
Varun Khanna
Frédéric Lemoine
Damien Mornico
2018-03-19 09:30:00 2018-09-23 17:00:00 Europe/Paris Analyse de séquences OBJECTIFS : Les biologistes sont régulièrement confrontés à des gènes (ou des protéines) de fonctions inconnues ou mal annotés. Dans ce contexte, maîtriser quelques techniques basiques d’analyse de séquences peut se révéler d’une aide […] Institut Pasteur, Rue du Docteur Roux, Paris, France
09:00
10
May 2016
Course

Morning session – Introduction to NGS data analysis

The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […]
Claudia Chica
Frédéric Lemoine
Jack Christophe Cossec
Hugo Varet
Anne Biton
Natalia Pietrosemoli
Guilhem Janbon
Varun Khanna
Rachel Torchet
Pierre Lechat
Amine Ghozlane
Nicolas Maillet
Axel Cournac
2016-05-10 09:00:00 2016-06-28 12:00:00 Europe/Paris Morning session – Introduction to NGS data analysis The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […] 28 Rue du Dr Roux, Paris, France

Projects

Project
Ongoing
7 Members

Translation and Ribosome rescue

Micheline Fromont-Racine (PI)

Translation involves four main steps: initiation, elongation, termination and recycling. Each step is highly controlled and can be modulated depending on the mRNA characteristics. The first step begins with the binding of eIF3 to […]
Project
Completed
3 Members

De novo assembly for integration into MicroScope/MaGe platform

Laurent Debarbieux (PI)

To perform the assembly of a bacterial genome from Illumina sequencing in order to submit it to the MicroScope/MaGe platform of Genoscope.
Project
Ongoing
5 Members

Variant detection on NGS data

Laurent Debarbieux (PI)

The goal of this project is to set sequence analysis tools to evaluate the frequency of mutations within a pool of bacteriophage genomes sequenced by NGS.

Publications

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