The Quantitative Biology program of the Institut Pasteur is intended to facilitate research and education at the interface of biology and the more quantitative sciences. One of the major aims of Quantitative Biology is thus to […]
LabEx IBEID – Integrative Biology of Emerging Infectious Diseases
Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart, is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs). […]
ERC-2015-StG Regulation of cell size and shape in bacteria
Our lab has received an ERC starting grant to investigate cell-size and shape regulation in bacteria. The grant will support our major research topic. See the other projects for more details.
Welcome to the club! Welcome to Microfluidics@Pasteur! Our goal is to serve as the major entry point to all the scientists on the campus (beginners and experts) interested in undertaking projects where microfluidics is involved. Our […]
Regulation of cell volume and single-cell physiology
Bacterial physiology has traditionally been studied on the population level. However, novel single-cell experiments reveal that there is significant cell-to-cell variation in quantities like growth rate, gene expression, intracellular metabolite concentrations, energy levels, etc., […]
2020The extracellular matrix protein TasA is a developmental cue that maintains a motile subpopulation within Bacillus subtilis biofilms., Sci Signal 2020 05; 13(632): .
2020Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi-enzyme complexes in Escherichia coli., EMBO J. 2020 Mar; 39(5): e102246.
2020The transpeptidase PBP2 governs initial localization and activity of the major cell-wall synthesis machinery in E. coli., Elife 2020 Feb; 9:e50629 .
2020Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects, eLife 2020;9:e51998.
2019Bacteria control cell volume by coupling cell-surface expansion to dry-mass growth, biorRxiv 2019; 769786.
2019Transpeptidase PBP2 governs initial localization and activity of major cell-wall synthesis machinery in Escherichia coli, BioRxiv (2019) 716407. doi:10.1101/716407..
2019Bacillus subtilis cell diameter is determined by the opposing actions of two distinct cell wall synthetic systems, Nat Microbiol 2019 May;.
2018Tuning dCas9’s ability to block transcription enables robust, noiseless knockdown of bacterial genes, Molecular Systems Biology (2018) 14, e7899.
2018Recent advances in understanding how rod-like bacteria stably maintain their cell shapes, F1000Research 2018, 7(F1000 Faculty Rev):241.
2017Mechanical strain-sensing implicated in cell shape recovery in Escherichia coli, Nat. Microbio. 2017; 2:17115.
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