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Targeting Malaria Epigenetics
Ludovic Halby (PI)
Malaria is a tropical disease due to a parasite named Plasmodium. It is a global health problem, still causing more than 450.000 deaths each year (mostly African children) and over 200 million infections (http://www.who.int/malaria/en/). […]
2014ZIPCO, a putative metal ion transporter, is crucial for Plasmodium liver-stage development, EMBO Mol Med 2014 Nov;6(11):1387-97.
2011Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa, Cell Host Microbe 2011 Dec;10(6):591-602.
2011The novel putative transporter NPT1 plays a critical role in early stages of Plasmodium berghei sexual development, Mol. Microbiol. 2011 Sep;81(5):1343-57.
2009LISP1 is important for the egress of Plasmodium berghei parasites from liver cells, Cell. Microbiol. 2009 Sep;11(9):1329-39.
2009Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites, J. Exp. Med. 2009 Apr;206(4):953-66.
2007Serial Analysis of Gene Expression in Plasmodium berghei salivary gland sporozoites, BMC Genomics 2007 Dec;8:466.
2007Imaging malaria sporozoites in the dermis of the mammalian host, Nat Protoc 2007;2(7):1705-12.
2007In vivo imaging of malaria parasites in the murine liver, Nat Protoc 2007;2(7):1811-8.
2006The murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells, Mol. Cell. Biol. 2006 May;26(9):3541-9.
2004The elusive malaria sporozoite in the mammalian host, Mol. Microbiol. 2004 Oct;54(2):298-306.
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