Nathalie has been working at Pasteur Institute since 1988. In the beginning she used to work on the mechanism of transcription in Henri BUC’s lab with Annie KOLB. Then in 1992 she joined Maurice HOFNUNG’s lab to work first on the structure and the function of the protein MalE and then on proteins – proteins interactions with Jean Michel BETTON. She further developed her expertise in Michel GOLDBERG’s unit and integrated Pedro ALZARI’s unit in 2006 where she studied with Jean Michel BETTON protein folding and protein quality control system in the periplasm of E. coli, as well as the mechanism of the regulation of an envelope stress response in E. coli. She joined our lab in June 2014, first learning more about cyanobacteria and cyanobacterial maintenance with Thérèse COURSIN, and now takes care of a part of the PCC strains. Nathalie is also working using molecular biology on the research projects of the lab dealing with evolution and natural products.
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Project 2- New molecular pathways driving cytokinetic abscission
Arnaud Echard (PI)
All known proteins required for cytokinetic abscission are enriched in the midbody, the central part of the intercellular bridge that connects the daughter cells after furrow ingression. We and others discovered that, in most […]
2023MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis, Developmental Cell, 2023, 58, pp.1-18. ⟨10.1016/j.devcel.2023.09.010⟩.
2021The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface., Curr Biol 2021 May; 31(10): 2203-2213.e5.
2019Physiological and evolutionary implications of tetrameric photosystem I in cyanobacteria, Nat Plants 2019 Dec;5(12):1309-1319.
2019Effect of tolytoxin on tunneling nanotube formation and function, Sci Rep 2019 Apr;9(1):5741.
2018A Unique Biosynthetic Pathway in Bloom-Forming Cyanobacterial Genus Microcystis Jointly Assembles Cytotoxic Aeruginoguanidines and Microguanidines, ACS Chem. Biol. 2019 Feb;4(1):67–75.
2018Terminal olefin profiles and phylogenetic analyses of olefin synthases in diversified cyanobacterial species, Appl. Environ. Microbiol. 2018 Jun;84(13):e00425-18.
2017Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927, ACS Chem Biol 2017 Jul; 12(7): 1796-1804.