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© Therese Couderc, Marc Lecuit
Member: Post-doc

Melissa Hanson

Scientific Fields
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Timeline

CV

Education

2014 PhD, Massachusetts Institute of Technology, Cambridge, MA, USA
2005 Bachelor of Science, University of Utah, Salt Lake City, UT, USA

Current Position

Post-doctoral fellow, Institut Pasteur, Paris, France

Previous Positions

2009 – 2014 PhD Student (Darrell J. Irvine Lab), Massachusetts Institute of Technology, Cambridge, MA, USA
2006 – 2009 Undergraduate Research Assistant (Patrick F. Kiser lab), University of Utah, Salt Lake City, UT, USA

Fellowships and Awards

2009 – 2012 National Science Foundation Graduate Student Research Fellowship
2005 – 2009 University of Utah Full Tuition Merit Scholarship

Publications

Irvine DJ, Hanson MC, Rakhra K, & Tokatlian T
Synthetic Nanoparticles for Vaccines and Immunotherapy
Chemical Reviews Published online: 8 July 2015.

Hanson MC, Crespo MP, Abraham W, Moynihan K, Szeto GL, Chen SH, Melo MB, Mueller S, Irvine DJ
Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants
J Clin Invest 2015 125(6): 2532-2546

Hanson MC, Abraham W, Crespo MP, Chen SH, Liu H, Szeto GL, Kim M, Reinherz EL, Irvine DJ
Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides
Vaccine 2015 33: 861-868 

Hanson MC, Bershteyn A, Crespo MP, Irvine DJ 
Antigen Delivery by Lipid-enveloped PLGA Microparticle Vaccines Mediated by In Situ Vesicle Shedding
Biomacromolecules 2014 15(7): 2475-2481 

Wang S, Mata-Fink J, Kriegsman B, Hanson MC, Irvine DJ, Burton DR, Wittrup KD, Mehran K, Chakraborty AK 
Sequential immunization with HIV variants may steer affinity maturation toward broadly neutralizing antibodies
Cell 2015 160(4): 785-797

Mikyung Kim M, Song L, Moon JJ, Sun ZJ, Bershteyn A, Hanson MC, Cain D, Goka S, Kelsoe G, Wagner G, Irvine DJ, Reinherz E
Immunogenicity of Membrane-bound HIV-1 gp41 Membrane-proximal External Region (MPER) Segments Is Dominated by Residue Accessibility and Modulated by Stereochemistry. 
Biol Chem 2013 288: 31888-31901

Mata-Fink J, Kriegsman B , Yu HX, Zhu HN, Hanson MC, Irvine DJ, Wittrup KD 
Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed Yeast
Molecular Biology 2013 425(2): 444-456 

Bershteyn A, Hanson MC, Crespo MP, Moon JJ, Li AV, Suh H, Irvine DJ
Robust IgG Responses to Nanograms of Antigen using a Biomimetic Lipid-coated Particle Vaccine
Controlled Release 2012 157(3): 354-365 

Jay JI, Langheinrich K, Hanson MC, Mahalingam A, Kiser PF
Unequal Stoichiometry between Crosslinking Moieties Affects the Properties of Transient Networks Formed by Dynamic Covalent Crosslinks 
Soft Matter 2011 7(12): 5826-5835

Jay JI, Shukair S, Langheinrich K, Hanson MC, Cianci GC, Johnson TJ, Clark MR, Hope TJ, Kiser PF
Modulation of Viscoelasticity and HIB Transport as a Function of pH in a Reversible Crosslinked Hydrogel
Adv Func Mater 2009 19(18): 2969-2977 

Roberts MC, Mahinghan AP, Hanson MC, Kiser PF.
Chemorheology of Phenylboronate-Salicylhydroxamate Cross-Linked Hydrogel Networks with a Sulfonated Polymer Backbone
Macromolecules 2008 41(22): 8832-884

Roberts MC, Hanson MC, Massey AP, Karren EA, Kiser PF
Dynamically Restructuring Hydrogel Networks Formed with Reversible Covalent Crosslinks 
Adv Mater 2007 19(18): 2503-7