Dr. Mathieu Angin received his PhD in Immunology in 2008 from the University of Nantes, France. During his training at the Center of Research in Transplantation and Immunology, he worked on the induction of tolerance in transplantation through T cell costimulatory blockade under the supervision of Dr. Brigitte Le Mauff. In 2009, he joined the group of Dr. Marylyn Addo at the Ragon Institute of MGH, MIT and Harvard in Boston, USA. There he worked as a post-doctoral fellow for 5 years on the understudied but important role of regulatory T cells in the context of HIV-1.
In 2014, he came back to France to work as a post-doctoral fellow at the Institut Pasteur in the team of Dr. Asier Saez-Cirion to work on the characterization of HIV-1 specific CD8+ T cell gene expression profiles in HIV controllers with the help of the French research agency ANRS. Thanks to a Marie Skłodowska-Curie Individual Fellowship from the European Commission and the support of SIDACTION, he investigated the role of metabolism in the control of HIV infection by CD8+ T cells. Understanding the mechanisms leading to an efficient CD8+ T cell response against the virus could lead to the development of new pharmacological tools to develop controller-like responses in HIV-infected progressors.