Projects
Former Teams
Publications
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2017The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β2-Microglobulin through Distinct Binding Sites, Biochemistry 2017 Aug;56(30):3945-3961.
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2016Automated structure modeling of large protein assemblies using crosslinks as distance restraints, Nat. Methods 2016 Jun;13(6):515-20.
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2015Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation, PLoS Pathog. 2015 Sep;11(9):e1005162.
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2014An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps, Bioinformatics 2015 May;31(9):1490-2.
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2013Structure-Based, Rational Design of T Cell Receptors, Front Immunol 2013;4:268.
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2012T-cell receptors binding orientation over peptide/MHC class I is driven by long-range interactions, PLoS ONE 2012;7(12):e51943.
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2011TCRep 3D: an automated in silico approach to study the structural properties of TCR repertoires, PLoS ONE 2011;6(10):e26301.
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2008Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues, Proc. Natl. Acad. Sci. U.S.A. 2008 Sep;105(39):15010-5.
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2007A novel population of human melanoma-specific CD8 T cells recognizes Melan-AMART-1 immunodominant nonapeptide but not the corresponding decapeptide, J. Immunol. 2007 Dec;179(11):7635-45.