I currently work at the “Architecture and dynamics of biological macromolecules” lab at Pasteur Institute. We use molecular biology and biochemical tools to study the shape and function of polymerases.
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STRUCTURAL BASIS FOR DNA REPLICATION AND REPLICATION-COUPLED DNA REPAIR IN ARCHAEA
Ludovic Sauguet (PI)
One fundamental challenge of cells is to accurately copy their genetic material for cell proliferation. DNA replication is performed by sophisticated multi-protein machines, which must synthesize DNA continuously and copy it accurately at the […]