I currently work at the “Architecture and dynamics of biological macromolecules” lab at Pasteur Institute. We use molecular biology and biochemical tools to study the shape and function of polymerases.
STRUCTURAL BASIS FOR DNA REPLICATION AND REPLICATION-COUPLED DNA REPAIR IN ARCHAEA
One fundamental challenge of cells is to accurately copy their genetic material for cell proliferation. DNA replication is performed by sophisticated multi-protein machines, which must synthesize DNA continuously and copy it accurately at the […]