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Understanding viral attenuation for the rationalization of vaccine design
Nolwenn Jouvenet (PI)
Vaccination is one of the greatest successes of modern medicine. The first generation of viral vaccines relied on empiric attenuation by repeated passage in animals and/or cultured cells. A successful attenuation process eliminates virulence […]
2019The Polyphenol-Rich Extract from an Endemic Medicinal Plant from Reunion Island, Inhibits the Early Stages of Dengue and Zika Virus Infection, Int J Mol Sci 2019 Apr;20(8).
2017Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells, EMBO J. 2017 Jun;36(12):1653-1668.
2017Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses, Cell Rep 2017 Jan;18(2):324-333.
2015Mechanisms of HIV-1 Nucleocapsid Protein Inhibition by Lysyl-Peptidyl-Anthraquinone Conjugates, Bioconjug. Chem. 2016 Jan;27(1):247-56.
2015Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons, Sci Signal 2015 Mar;8(366):ra25.