Laetitia completed her PhD in 2005 at the Pasteur Institute, working on Plasmodium falciparum. After a postdoc on pathogenic E. coli at Imperial College London, she came back to parasites and to Paris, using the trypanosome and its flagellum as a model to study primary ciliary dyskinesia, a genetic disease affecting cilia and flagella. In collaboration with Unité Inserm 933 (Hôpital Trousseau, directed by Serge Amselem) her work highlighted the importance of cytoplasmic preassembly of flagellar components. During her time in the lab (2007-2012), she investigated the mechanisms of flagellar growth, wondering whether a flagellum is built like a Lego tower, with new material being added at the distal tip. Laetitia is now a lecturer at the University Pierre and Marie Curie.
2017Flagellar incorporation of proteins follows at least two different routes in trypanosomes, Biol. Cell 2018 110(2):33-47.
2014Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics, Mol. Cell Proteomics 2014 Jul;13(7):1769-86.