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© Artur Scherf
Scanning Electron Microscopy of Red Blood Cell infected by Plasmodium falciparum.
Member: Post-doc - Alumni

Julien Guizetti

CV

Career

From 12/2011 until 30/11/16
Institut Pasteur, Paris (France)
Postdoctoral researcher at the Scherf lab, Department of Parasites and Insect Vectors
“Identifying novel regulators in Plasmodium falciparum antigenic variation”

04/2007 – 09/2011    
ETH, Zurich (Switzerland)
PhD project at the Gerlich lab, Institute of Biochemistry. Phd degree in May 2011
“Mechanism of cytokinetic abscission in HeLa cells”

01/2006 – 09/2006    
McGill University, Montreal (Canada)
Diploma thesis project at the Vogel lab, Cell Biology Department.
“Regulation of Budding Yeast Gamma-Tubulin Influences Astral Microtubule Number and Length”

08/2003 – 12/2005    
ESBS (École Supérieure de Biotechnologie Strasbourg)
Tri-national university at Strasbourg (France), Basel (Switzerland), Karlsruhe & Freiburg (Germany)
Engineer’s degree in Biotechnology in September 2006.

06/2001 – 07/2003    
University of Karlsruhe (Germany)
Studies in biology, second year’s university degree in July 2004 (Vordiplom).

06/2000 – 05/2001    
DKFZ (German Cancer Research Centre), Heidelberg (Germany)
Alternative service as Technical Assistant at the Zentgraf lab.

Research publications

Zhang, Q., Siegel, T. N., Martins, R. M., Wang, F., Cao, J., Gao, Q., Cheng, X., Jiang, L., Hon, C. C., Scheidig-Benatar, C., Sakamoto, H., Turner, L., Jensen, A. T., Claes, A., Guizetti, J., Malmquist, N. A., and Scherf, A. (2014). Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria. Nature 513, 431-435.

Guizetti, J., Martins, R. M., Guadagnini, S., Claes, A., and Scherf, A. (2013). Nuclear Pores and Perinuclear Expression Sites of var and Ribosomal DNA Genes Correspond to Physically Distinct Regions in Plasmodium falciparum. Eukaryot Cell 12, 697-702.

Guizetti, J., Schermelleh, L., Mantler, J., Maar, S., Poser, I., Leonhardt, H., Muller-Reichert, T., and Gerlich, D. W. (2011). Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. Science 331, 1616-1620.

Guizetti, J., Mantler, J., Muller-Reichert, T., and Gerlich, D. W. (2010). Correlative time-lapse imaging and electron microscopy to study abscission in HeLa cells. Methods Cell Biol 96, 591-601.

Lacroix, B., van Dijk, J., Gold, N. D., Guizetti, J., Aldrian-Herrada, G., Rogowski, K., Gerlich, D. W., and Janke, C. (2010). Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. J Cell Biol 189, 945-954.

Lekomtsev, S., Guizetti, J., Pozniakovsky, A., Gerlich, D. W., and Petronczki, M. (2010). Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells. J Cell Sci 123, 1395-1400.

Steigemann, P., Wurzenberger, C., Schmitz, M. H., Held, M., Guizetti, J., Maar, S., and Gerlich, D. W. (2009). Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell 136, 473-484.

Reviews

Guizetti, J., and Scherf, A. (2013). Silence, activate, poise and switch! Mechanisms of antigenic variation in Plasmodium falciparum. Cell Microbiol 15, 718-726.

Guizetti, J., and Gerlich, D. W. (2012). ESCRT-III polymers in membrane neck constriction. Trends Cell Biol 22, 133-140.

Guizetti, J., and Gerlich, D. W. (2010). Cytokinetic abscission in animal cells. Semin Cell Dev Biol 21, 909-916.

Selected Meetings & Courses

04/2015    “The Art of Leadership”, EMBO lab management course, 3 days, Heidelberg
05/2014    BioMalPar Conference, EMBL Heidelberg – Poster.
04/2014    Paractin meeting, Mexico City – Talk
10/2013    EMBO Meeting “Nuclear Strucutre and Dynamics”, Isles sur Sorgues – Poster
09/2013    “Advanced Imaging Techniques for Malaria Researchers” workshop, Sydney – Student
06-08/2012    “Biology of Parasitism” course at Marine Biology Lab, Woods Hole – Student.
05/2012    BioMalPar Conference, EMBL Heidelberg – Talk & Poster.
11/2010    ASBMB Meeting “ESCRTs in Health and Disease”, Salt Lake City – Talk & Poster
(Recipient of poster prize and travel grant).
06/2010    EMBO Meeting “Microtubules”, EMBL Heidelberg – Poster.
08/2009    CIMST Meeting, ETHZ – Talk.
07-08/2009    Summer lab, MBL Woods Hole – Electron microscopy of intercellular bridges.
09/2008    Young Scientist Meeting, Heidelberg – Talk & Poster.
06-07/2007    Summer lab, MBL Woods Hole – Electrophysiology of dividing HeLa cells.

Languages    

German  Native language.
French    2nd Native language.
English    Very good command of English, both spoken and written.

Training periods and practical work

06/2005-07/2005 University of Freiburg
Summer internship at the Beyer lab, Arabidopsis biochemistry (6 weeks).

03/2005-04/2005 University of Freiburg
Practical work in plant genetics (6 weeks).

06/2004-07/2004    EMBL (European Molecular Biology Laboratory), Heidelberg
Summer internship at the Karsenti lab, Xenopus microtubule cell biology (7 weeks).

01/2004-02/2004 Biozentrum Basel
Practical work in microbiology (6 weeks).

Fellowships & Awards    

Human Frontier Science Program (HFSP) postdoctoral fellow; Long-Term fellowship June 2012-2015.

ETH medal 2012 for an outstanding PhD thesis

Postdoctoral fellowship for prospective researchers by the Swiss National Science Foundation (SNF) December 2011-2012.

DAAD grant during diploma thesis in 2006.

Committees    

Organizer of “1st Postdoc Days”, a two days career workshop, Institut Pasteur 2013.

Organizer of ETH Biology department PhD Summer school 2008.

PhD representative at Institute of Biochemistry, ETH 2008-2009.

Political interests    

Volunteering project November 2011, “Bed net distribution and Malaria education in rural Uganda” (julieninuganda.wordpress.com)

Participant at “Bright European Student’s Conference” April 2005 in Leuven, Belgium.

Sports    
1994 – 2011 active member in a field hockey club.

Since 2012 active member in a badminton club.

Publications

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