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Role of ncRNAs in C. difficile physiology and regulatory networks
Olga Soutourina (PI)
In bacteria, it is increasingly recognized that ncRNAs play a critical role in adaptive responses and in various metabolic, physiological and pathogenic processes. In Clostridium difficile, by combining in silico analysis, RNAseq and genome-wide […]
2017Identification of c-di-GMP-Responsive Riboswitches, Methods Mol. Biol. 2017;1657:377-402.
2015Cyclic-di-GMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage, J. Biol. Chem. 2015 Aug;.
2013Characterization of the SigD regulon of C. difficile and its positive control of toxin production through the regulation of tcdR, PLoS ONE 2013;8(12):e83748.
2013Genomic and expression analysis of the vanG-like gene cluster of Clostridium difficile, Microbiology (Reading, Engl.) 2013 Jul;159(Pt 7):1510-20.
2011Clostridium difficile has an original peptidoglycan structure with a high level of N-acetylglucosamine deacetylation and mainly 3-3 cross-links, J. Biol. Chem. 2011 Aug;286(33):29053-62.
2010Characterization of Acp, a peptidoglycan hydrolase of Clostridium perfringens with N-acetylglucosaminidase activity that is implicated in cell separation and stress-induced autolysis, J. Bacteriol. 2010 May;192(9):2373-84.