Frida holds a PhD in Neuroscience and works as a post-doctoral researcher at Pasteur. In the Zurzolo lab, she studies the mechanisms of protein spreading in experimental models of proteinopathies. As a neuroscientist, Frida is interested in addressing the role of different cells in the propagation of pathologies in the brain. She really enjoys observing astrocytes through the confocal microscope!
Prion-like proteins spreading in neurodegenerative diseases: role of Tunneling Nanotubes (TNTs)
Prion-like proteins spreading in neurodegenerative diseases (NDs): role of Tunneling Nanotubes (TNTs) NDs are protein conformational disorders linked to the propagation of protein misfolding in the brain in a prion-like manner. A seminal discovery […]
2017α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading, Acta Neuropathol. 2017 11;134(5):789-808.
2016Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes, EMBO J. 2016 10;35(19):2120-2138.