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Diversity and stability of eukaryotic transcripts
Alain Jacquier (PI)
We focus on RNA quality control mechanisms and their consequences for the cells. Our previous studies revealed, for example, unexpected properties of the transcription process, such as its high pervasiveness and the intrinsic bi-directionality […]
2018General Regulatory Factors Control the Fidelity of Transcription by Restricting Non-coding and Ectopic Initiation, Mol. Cell 2018 12;72(6):955-969.e7.
2015Quality control of transcription start site selection by nonsense-mediated-mRNA decay, Elife 2015;4.
2014Long open reading frame transcripts escape nonsense-mediated mRNA decay in yeast, Cell Rep 2014 Feb;6(4):593-8.
2012The yeast RPL9B gene is regulated by modulation between two modes of transcription termination, EMBO J. 2012 May;31(10):2427-37.