• Chemistry of Biomolecules • Organic Chemistry

Publications

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2016

Connell BJ, Sadir R, Baleux F, Laguri C, Kleman JP, Luo L, Arenzana-Seisdedos F, Lortat-Jacob H, Heparan sulfate differentially controls CXCL12α- and CXCL12γ-mediated cell migration through differential presentation to their receptor CXCR4, Sci Signal 2016 Nov;9(452):ra107.
2016

Ariën KK, Baleux F, Desjardins D, Porrot F, Coïc YM, Michiels J, Bouchemal K, Bonnaffé D, Bruel T, Schwartz O, Le Grand R, Vanham G, Dereuddre-Bosquet N, Lortat-Jacob H, CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge, Sci Rep 2016 Oct;6:34829.
2014

Migliorini E, Thakar D, Sadir R, Pleiner T, Baleux F, Lortat-Jacob H, Coche-Guerente L, Richter RP, Well-defined biomimetic surfaces to characterize glycosaminoglycan-mediated interactions on the molecular, supramolecular and cellular levels, Biomaterials 2014 Oct;35(32):8903-15.
2013

Noya V, Bay S, Festari MF, García EP, Rodriguez E, Chiale C, Ganneau C, Baleux F, Astrada S, Bollati-Fogolín M, Osinaga E, Freire T, Mucin-like peptides from Echinococcus granulosus induce antitumor activity, Int. J. Oncol. 2013 Sep;43(3):775-84.
2012

Rueda P, Richart A, Récalde A, Gasse P, Vilar J, Guérin C, Lortat-Jacob H, Vieira P, Baleux F, Chretien F, Arenzana-Seisdedos F, Silvestre JS, Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions, Circulation 2012 Oct;126(15):1882-95.
2012

Denoyer A, Godefroy D, Célérier I, Frugier J, Degardin J, Harrison JK, Brignole-Baudouin F, Picaud S, Baleux F, Sahel JA, Rostène W, Baudouin C, CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension, PLoS ONE 2012;7(6):e37873.
2012

Coïc YM, Baleux F, Poyraz Ö, Thibeaux R, Labruyere E, Chretien F, Sobhani I, Lazure T, Wyplosz B, Schneider G, Mulard L, Sansonetti PJ, Marteyn BS, Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain, J. Biol. Chem. 2012 May;287(19):15916-22.
2012

Connell BJ, Baleux F, Coic YM, Clayette P, Bonnaffé D, Lortat-Jacob H, A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage, Chem. Biol. 2012 Jan;19(1):131-9.
2011

Chiaravalli J, Fontan E, Fsihi H, Coic YM, Baleux F, Véron M, Agou F, Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO, Biochem. Pharmacol. 2011 Nov;82(9):1163-74.
2011

Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, Fujii N, Larochelle A, Dunbar CE, Broxmeyer HE, Frenette PS, Lapidot T, Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells, Leukemia 2011 Aug;25(8):1286-96.
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Françoise Baleux

• Chemistry of Biomolecules • Organic Chemistry

Patents

Glycoconjugates and their use as potential vaccines against infection by Shigella flexneri

Publications