Astrocytes marqués par des anticorps VHH anti-GFAP.
Des anticorps d'alpagas dirigés contre une protéine spécifique des astrocytes, la GFAP (Glial Fibrillary Acidic Protein), ont été obtenus à partir de camélidés immunisés. La partie VHH (partie de l'anticorps qui reconnaît l'antigène) a été exprimée sous forme recombinante chez Escherichia coli.
Specialized in Biotechnology and Cancer Biology, I am working on understanding VHHspenetration in the brain and cells then to be optimized and to develop new strategies for potential drugs (Neurodegenerative disorders, Cancers….)
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