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© Christelle Durand
Microscopie d'un neurone. Le marquage jaune montre les synapses.
Scientific Fields
Diseases
Organisms
Applications
Technique

About

The genetic architecture underlying autism is highly complex. The combined effect of more than 100 rare deleterious variants, as well as common variants, are distributed throughout the genome. How these genetic risks for autism shape anatomical and functional brain connectivity remain poorly understood.

I will investigate the impact of such molecular proxies for autism on brain measures – and use them to disentangle mechanisms at play in this heterogeneous neurodevelopmental condition.

I did a Ph.D. in Neuroscience (2015-2020) co-directed by Sébastien Jacquemont (Geneticist, Sainte Justine Hospital) and Pierre Bellec (Associate professor in Computer Science, CR-IUGM) at the University of Montreal, Canada: Mapping genome-wide neuropsychiatric mutation effects on functional brain connectivity: Copy number variants delineate dimensions contributing to autism and schizophrenia. More information:

https://claramoreau9.github.io/