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CV
Birth date : June 21 1987
Nationality : French
Present Position :
10/2015 : Postdoctoral fellow – Lymphopoiesis unit (Inserm U668) Institut Pasteur – Paris
Education :
10/2011 – 9/2015 : PhD – Lymphopoiesis unit (Inserm U668) Institut Pasteur – Paris under Dr Ana Cumano’s supervision. Thesis subject : Molecular regulation of lymphoid commitment in murine fetal liver. Ecole doctorale B3MI – Paris Diderot university.
11/2010 – 1/2011 : Theoretical and practical courses M2 Immunologie Approfondie, Institut Pasteur Paris Mention Bien.
9/2009 – 6/2011 : Master I et II “Biologie Moléculaire et Cellulaire” Pierre et Marie Curie University (UPMC Sorbonne University) speciality Immunology.
Master II subject : Study of heterogeneity in CLP compartment in murine fetal liver, under Dr. Ana Cumano’s supervision – Lymphopoiesis unit (INSERM U668), Institut Pasteur Paris. Mention Très Bien (ranked 6th on 20)
9/2006 – 6/2009 : Bachelor “Sciences de la Vie” speciality Biochemistry – Pierre et Marie Curie University (UPMC Sorbonne University).
Professional Experiences :
1/2010 – 5/2010 : Master I training – Lymphopoiesis unit (INSERM U668), Institut Pasteur Paris, under Dr. Antonio Bandeira’s supervision (DR2 CNRS). Study of regulatory T cell compartment in CCR7 KO mice.
Oral Communications and posters :
February 22-27, 2015 : Keystone Symposia Hematopoiesis 2015, Keystone Resort, Colorado USA. Poster : Molecular regulation of lymphoid commitment in fetal liver Common Lymphoid Progenitors. C. Berthault, C. Ramond, O. Burlen-Defranoux, S. Chea, G. Soubigou, R. Golub, P. Vieira and A. Cumano.
January 26-28, 2015 : Revive 4th Annual Consortium Meeting 2015, Château Saint-Just, Belle-Eglise, France. Poster : Molecular regulation of lymphoid commitment in fetal liver Common Lymphoid Progenitors. C. Berthault, C. Ramond, O. Burlen-Defranoux, G. Soubigou, P. Vieira and A. Cumano.
February 3-5, 2014 : Revive 3rd Annual Consortium Meeting 2014, Château Saint-Just, Belle-Eglise, France. Communication orale : Molecular regulation of early lymphoid commitment in Common Lymphoid Progenitors. C. Berthault, C. Ramond, O. Burlen-Defranoux, G. Soubigou, P. Vieira and A. Cumano.
November 4-7, 2013 : Annual Meeting of the French Society for Immunology 2013, Cité Internationale Universitaire, Paris, France. Communication orale : Molecular regulation of early lymphoid commitment in Common Lymphoid Progenitors. C. Berthault, C. Ramond, O. Burlen-Defranoux, G. Soubigou, P. Vieira and A. Cumano.
October 18, 2013 : 7th Translational Research Day, Institut Pasteur, Paris, France. Communication orale: Single cell gene expression analysis of early lymphoid progenitors. C. Berthault, C. Ramond, O. Burlen-Defranoux, G. Soubigou, P. Vieira and A. Cumano.
September 7-14, 2013 : Hydra IX – The European Summer School on Stem Cell Biology, Hydra, Greece. Poster : Molecular regulation of early lymphoid commitment in Common Lymphoid Progenitors. C. Berthault, C. Ramond, O. Burlen-Defranoux, G. Soubigou, P. Vieira and A. Cumano.
October 15-17, 2012 : Journées du département d’immunologie de l’Institut Pasteur, Palais des congrès Saint-Malo, France. Poster : Molecular regulation of early lymphoid commitment in Common Lymphoid Progenitors. C. Berthault, C. Ramond, O. Burlen-Defranoux, G. Soubigou, P. Vieira and A. Cumano
Awards and fellowships :
10/2015 : postdoctoral contract – Inserm (October 2015 – June 2016)
9/2014 : 4th year PhD fellowship – Ligue Contre Le Cancer (September 2014 – September 2015
9/2011 : PhD fellowship – MENRT du Ministère de l’enseignement supérieur et de la Recherche (September 2011 – September 2014).
Languages skills :
French : mother Language
English : fluent
Publications
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2019New Molecular Insights into Immune Cell Development, Annu. Rev. Immunol. 2019 Apr;37:497-519.
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2017Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis, Immunity 2017 Oct;47(4):680-696.e8.
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2017Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver, Nat. Immunol. 2017 18(10):1139-1149.
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2016Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases, J. Clin. Invest. 2016 Apr;126(4):1525-37.
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2016Single-Cell Gene Expression Analyses Reveal Heterogeneous Responsiveness of Fetal Innate Lymphoid Progenitors to Notch Signaling, Cell Rep 2016 February 16;14:1500-1516.
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2015Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays, J Vis Exp 2015;(100).
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2013Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus, Nat. Immunol. 2014 Jan;15(1):27-35.
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2013Critical role of TCR specificity in the development of Vγ1Vδ6.3+ innate NKTγδ cells, J. Immunol. 2013 Aug;191(4):1716-23.
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2012Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors, J. Immunol. 2012 Oct;189(8):3822-30.