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  • Associate Professor
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  • Full Professor
  • Graduate Student
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  • PhD Student
  • Physician
  • Post-doc
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  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
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  • Honorary President of the Departement
  • Labex Coordinator
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CV

Recurrent enteric infections in children of low income countries, chronic inflammatory bowel diseases, nosocomial diseases, myelosuppressive and immunosuppressive therapies are, among others, clinical situations that require strong boosting of mucosal innate defenses to respectively avoid luminal bacterial overgrowth causing malnutrition, chronic inflammation, opportunistic infection, and deadly translocation. Our challenge is to translate fundamental findings in the genetic and epigenetic regulation of antimicrobial mechanisms of the epithelium into drugs and interventions boosting their expression. In contract with the high-throughput screening platform of Institut Pasteur Korea, and in collaboration with Sanofi and BioMérieux, we aim to identify molecules from the pharmacopoeia inducing strong expression of epithelial antimicrobial molecules, without triggering significant inflammation.

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