Biofilm formation on medical devices is associated with hospital-acquired (nosocomial) infections. Due to biofilms’ high tolerance to antibiotics, classical treatments lack efficacy, and removal of the biofilm-contaminated device is often the only therapeutic option. […]
In vivo Study of Biofilm-Associated Catheter Infections
We developed a clinically relevant in vivo model of catheter-associated biofilm infections to design new and efficient biofilm-eradication approaches applicable to contaminated totally implantable venous access port (TIVAP) catheters. Key publication• Chauhan, A., D. Lebeaux, B. Decante, I. Kriegel, M.C. […]
2017Comparative Analysis of Bacterial Community Composition and Structure in Clinically Symptomatic and Asymptomatic Central Venous Catheter., mSphere, in press.
2016Study of in vivo catheter biofilm infections using pediatric central venous catheter implanted in rat, Nature Protocol 2016 Mar;11(3):525-41Epub 2016 Feb 18.