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Chromosight: A computer vision program for pattern detection in chromosome contact maps
Romain Koszul (PI)
Chromosomes of all species studied so far display a variety of higher-order organizational features such as domains, loops, or compartments. Many of these structures have been characterized from the genome-wide contact maps generated by […]
2020Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects, eLife 2020;9:e51998.
2019Transpeptidase PBP2 governs initial localization and activity of major cell-wall synthesis machinery in Escherichia coli, BioRxiv (2019) 716407. doi:10.1101/716407..
2018A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9, Nat Commun. 2018 May 15;9(1):1912. doi: 10.1038/s41467-018-04209-5.
2018Tuning dCas9’s ability to block transcription enables robust, noiseless knockdown of bacterial genes, Molecular Systems Biology (2018) 14, e7899.