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© Research
Member: Deputy Director of Center

Angèle Bénard

About

I am originally an infectious disease scientist who has developed a genuine interest in bioinformatics. I believe that the use of big data and computational methods applied to biology will be a leverage point in our fight to tackle the current global health inequities. Moreover, the development of novel bioinformatics tools will be decisive for addressing the new, yet imminent health challenges that the world population will be facing in a near future. These include but are not restricted to emerging diseases or antibiotic resistance.

I am hoping to strengthen C3BI research, teaching, and service capacity to make it a critical and powerful collaborative resource for all the biology research undertaken at the Pasteur Institute. In addition, my vision is that C3BI is bound to play a pivotal and influential role in the computational biology landscape at the national and international level.

My missions are diverse, I am committed to

  • Identifying opportunities and facilitating big scale projects including the support for grants application 
  • Ensuring the visibility of C3BI and fostering collaborations in the C3BI at the national and international level
  • Fostering multiple partnerships with international bioinformatics structures 
  • Creating synergies among the C3BI research units, facilitating collaborations with other research units within Pasteur Institute Campus and with the CNRS.
  • Contributing to the design and coordination of teaching and training programmes at the Pasteur Paris Campus and within the International Network of Pasteur Institutes.
  • Strengthening bioinformatics capacity building and outreach within the International Network of Pasteur Institutes
  • Managing the smooth operation (communication, activity reports, budgeting, human resources) of the C3BI within the Pasteur Institute and the CNRS.  

CV

EXPERIENCE:

Senior Staff Scientist at the Wellcome Trust Sanger Institute, Hinxton (UK), 2015 – 2018 

Analysis of host-pathogen interactions of infectious diseases of global health relevance (chlamydia, shigellosis, cholera, tuberculosis) at the genomic, phenotypic and epidemiological level.

  • RNAseq and whole genome sequencing analysis of persister mutants of Mycobacterium tuberculosis
  • MLPA, development of a new diagnostic and molecular epidemiological tool for Vibrio cholerae outbreaks
  • Phylogenetic analysis of Shigella sonnei outbreaks by whole-genome sequencing.
  • Use of intestinal organoids as an innovative model of infection for studying persistence, host-pathogen interactions and genetic diversity of Chlamydia trachomatis infection.
  • Whole genome sequence of Vibrio cholerae directly from filter paper

Research Fellow at Albert Einstein College of Medicine September (NY, USA), 2012 – 2014

  • research project focused on developing novel cost-effective mycobacteria based vaccine against tuberculosis.

Lecturer and tutor for students in the Master program of Tropical Medicine and International Health, Institut de la Francophonie pour les Maladies Tropicales (Laos),  2012 

Scientific collaborator at Swiss Tropical and Public Health Institute (CH), 2008 – 2012

Research activities focusing on immunology, host-pathogen interactions and molecular epidemiology of Mycobacterium ulcerans disease (“Buruli ulcer”)

  • Thermotherapy clinical testing
  • Development of diagnostic tests
  • Seroepidemiology and host factors
  • Buruli ulcer mouse model development
  • Stop Buruli Consortium management (UBS Optimus Foundation)

Ph.D. student at University of Basel, 2004 – 2008

  • Regulatory T cell development and tolerance in mice

Research Assistant at Benaroya Research Institute (WA, USA), 2003 

  • Characterization of the role of the FoxP3 gene product, Scurfin, in regulatory T cells.

EDUCATION:

Master of Business Administration (M.B.A.), International Health Management, 2013 – 2016, Swiss Tropical and Public health institute (CH)

Ph.D., Cellular and Molecular Biology, 2004 – 2008, University of Basel

 MSc, Molecular and Cellular Biology; Biotechnology, 2003, Louis Pasteur University, Strasbourg (FR)

Engineer Diploma in Biotechnology, 2000 – 2003, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg (FR)

Publications

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