Projects
Publications
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2020Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis., Elife 2020 Feb; 9(): .
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2019The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation, Nat Commun 2019 07;10(1):3005.
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2019Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase, Sci Rep 2019 Mar;9(1):3947.
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2019Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase, Sci Rep 2019 Mar;9(1):3947.
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2018A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase., J Biol Chem 2018 04; 293(16): 6000-6010.
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2017Bulgecin A: The Key to a Broad-Spectrum Inhibitor That Targets Lytic Transglycosylases., Antibiotics (Basel) 2017 Feb; 6(1): .
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2017N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes, Nat Microbiol 2017 Feb;2:17005.
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2014Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members., Acta Crystallogr D Biol Crystallogr 2014 Oct; 70(Pt 10): 2631-9.
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2013The dynamics of peptidoglycan structure and function: conference report on the 3rd Great Wall Symposium, Res. Microbiol. 2014 Jan;165(1):60-7.
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2013De-O-acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis., Mol Microbiol 2013 Mar; 87(5): 1100-12.
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