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© Romain Levayer, Institut Pasteur
Epithelial layer of the Drosophila pupal thorax (notum). White : cell contour (E-cadherin), pseudocolour : Dpp sensor.

About

Bio: After following a double cursus in bio-informatics during my first 2 years of bachelor, I switched to a biology cursus oriented in genetics and development. I was introduced to the drosophila model during my first internship in the team of Jean-Michel Gibert. During this internship at the IBPS I tried to analyse the regulation of the tan gene. I then followed a master called “Gene Cell and development” at the university of Paris-Saclay. I slowly leaned toward quantitative approaches and bio-imaging during my two years of master. Accordingly I got my first experience in microscopy in the lab of François Schweisguth in which I was analysing in vivo, in the drosophila eye, the signalling of Notch receptor. I pursue in that direction choosing the lab of Romain Levayer for my M2 internship. There I focus on understanding the orchestration of epithelial elimination by the effector caspase still using microscopy and coding. For that, I try to characterise the process of cell extrusion in the pupal notum and to decipher the steps affected by the caspase inhibition while trying to identify new caspases substrates required for cell extrusion.

Scientific interests: I am interested in how an organism, tissue or organ regulates its proper size and proportions and how homeostasis or the equilibrium between death and proliferation is maintained. More generally I’m interested in plasticity of living tissue and morphogenesis. I also like beautiful microscopy.

Hobbies: I love playing music in general but especially guitar. I enjoy playing basketball, occasionally running and reading.

Projects