Deciphering Human Innate Lymphoid Cell Biology
ILCs are early effectors of immunity and provide a means to rapidly respond to infection or inflammation, and are distinguished from T and B cells of the adaptive immune response. Three groups of ILCs […]
Innate lymphoid cells (ILC) are a newly described family of hematopoietic cells that lack antigen-specific receptors but can be activated to promptly produce large amounts of cytokines (including interleukin (IL)-5, -13, -17A, -22, TNF-α […]
Mouse Model to Understand Innate Lymphoid Cell Biology
Mucosal homeostasis requires a delicate equilibrium between immune mechanisms and commensal microorganisms that impacts on the development and maintenance of critical physiological processes including digestion, metabolism or host defense. Several infectious or inflammatory disorders […]
2018ILC-poiesis: Ensuring tissue ILC differentiation at the right place and time, Eur. J. Immunol. 2018 Oct;.
2018A human immune system mouse model with robust lymph node development, Nat. Methods 2018 Aug;15(8):623-630.
2018A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity, Sci Immunol 2018 Jun;3(24).
2018Epigenome analysis links gene regulatory elements in group 2 innate lymphocytes to asthma susceptibility, J. Allergy Clin. Immunol. 2018 Feb;.
2017‘ILC-poiesis’: generating tissue ILCs from naïve precursors, Oncotarget 2017 Oct;8(47):81729-81730.
2017Developmental options and functional plasticity of innate lymphoid cells, Curr. Opin. Immunol. 2017 Feb;44:61-68.