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© Research
Job

Postdoctoral position – Mosquito-Virus Interactions

Scientific Fields
Diseases
Organisms
Applications
Technique
Application Deadline
30
Sep 2021
2021-09-30 8:00:00 2021-09-30 18:00:00 Europe/Paris Postdoctoral position – Mosquito-Virus Interactions We are looking for a post-doctoral researcher to come work with us on the interactions between Aedes aegypti mosquitoes and arboviruses at the single-cell level! Research Topic When a mosquito bites a human infected with […] "25-28 rue du Dr. Roux, 75015, Paris" Sarah Merkling sarah.merkling@pasteur.fr

We are looking for a post-doctoral researcher to come work with us on the interactions between Aedes aegypti mosquitoes and arboviruses at the single-cell level!

Research Topic

When a mosquito bites a human infected with an arbovirus, the viral infection cycle within the mosquito’s body begins. In the digestive track, virus particles enter and start replicating in midgut cells while the bloodmeal is digested. After a couple of days, the virus disseminates from the midgut to mosquito’s body, and reaches the salivary glands, through which it will be retransmitted to the next host.

A key step of the infection cycle is the initial infection of the midgut. However, very little is known about that step at the molecular and cellular level. For example, which midgut cells get infected with viruses, and what immune responses do they deploy? The goal of this postdoctoral project is to investigate those questions using an innovative approach based on single-cell RNA sequencing.

Requirements

  • Enthusiasm for the work and research area
  • Recent PhD in a relevant filed (e.g. vector biology, virology, immunology)
  • Experience in insect biology, microbiology (bacteriology, virology or parasitology) and molecular biology are  required
  • Experience with Next-Generation Sequencing (Wet lab) is preferred. Bioinformatics skills are a plus, but not required
  • Demonstrable publication record in peer-reviewed journals
  • Good scientific writing and communication skills in English
  • Enthusiasm for working within a team and an international research environment
  • Self-driven and able to work independently in an organized manner
  • Experience in working with students or research technicians is advantageous

Working at Institut Pasteur

This position is available for up to three years and starting in January/February 2022. It is funded by a grant from the French Research Agency (Agence Nationale pour la Recherche). Salary will be determined taking into account experience and according to the Institut Pasteur salary scale.

The Pasteur Institute is an international and dynamic research environment. The successful candidate will be supported in their career development by the PI and institutionally, and will be expected to independently advance the project, apply for grants, present their work at international conferences, and prepare publications.

Contact us !

If you are qualified, curious, and an inspired researcher who is interested in studying mosquito-virus interactions at the single-cell level, please send your CV, the names and contact information of three references, and a cover letter to sarah.merkling@pasteur.fr by 30th September 2021.

 

We are committed to foster a fair, inclusive and diverse work environment. Applicants will be evaluated  based on qualifications regardless of gender, gender identity, sexual orientation, race or disability.