One post-doctoral position is available in our lab. We are interested in the role of the stromal microenvironment in tissue homeostasis/repair, and how perturbation of this fundamental crosstalk fosters chronic diseases such as cancer, inflammatory diseases and autoimmune diseases. In this project, we will take advantage of unique genetic mice models to dissect the stroma-immune crosstalk in mucosal injury/inflammation (skin, intestine), determine the impact on disease pathogenesis, and identify the underlying cellular and molecular mechanisms. This study involves a wide range of techniques including mouse models for injury/inflammation, confocal microscopy, transcriptomic analysis, and lineage tracing/genetic depletion (Dulauroy, Nature Medicine 2012; Stzepourginski, PNAS 2017).
The successful candidate will have a PhD or MD/PhD, and a proven track record of achievement in immunology. Previous experience with multi-parametric flow cytometry and cell sorting will be appreciated. Highly motivated candidates with creative skills and strong interest in cross-disciplinary fields (immuno /stroma-vascular /neuronal) are particularly encouraged to apply.
This project is part of an ERC grant aiming at identifying new therapeutic approaches in inflammatory diseases, cancer and regenerative medicine. The position is available immediately. For more information or to apply, please send your complete CV, a motivation letter and contact information for 3 references, to: email@example.com