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© Institut Pasteur/Antoinette Ryter
Salmonella spp. Bactéries à Gram négatif, aérobies ou anaérobies facultatifs à transmission orofécale. Les salmonelles majeures (sérotype typhi et sérotype paratyphi) sont responsables des fièvres typhoïde et paratyphoïde chez l'homme uniquement ; les salmonelles mineures (sérotype typhimurium et sérotype enteritidis) sont impliquées dans 30 à 60 % des gastroentérites et toxiinfections d'origine alimentaire. Image colorisée.
Scientific Fields
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Application Deadline
02
Oct 2020
2020-10-02 8:00:00 2020-10-02 18:00:00 Europe/Paris Postdoctoral Position in Bacterial Genomics and Evolution A 2-year postdoctoral position (which may be renewed to up to two additional years) is available in the “Enteric Bacterial Pathogens” Unit at Institut Pasteur in Paris.   We are seeking an enthusiastic, talented, […] "25-28 rue du Dr. Roux, 75015, Paris" Francois-Xavier Weill francois-xavier.weill@pasteur.fr

A 2-year postdoctoral position (which may be renewed to up to two additional years) is available in the “Enteric Bacterial Pathogens” Unit at Institut Pasteur in Paris.

 

We are seeking an enthusiastic, talented, motivated postdoctoral research scientist with a strong experience of analyzing bacterial genomes and large genomic datasets to gain insights into the population structure of historical Enteropathogenic Escherichia coli (EPEC) and the emergence of antimicrobial resistance during the 1950s to the 1970s.

 

The successful candidate will work under the supervision of Dr. François-Xavier Weill (https://research.pasteur.fr/fr/member/francois-xavier-weill/).

 

The Enteric Bacterial Pathogens is a laboratory with both Research and Public Health activities (national laboratory surveillance of infections caused by Salmonella, Shiga toxin-producing E. coli, Shigella, and Vibrio). We use whole-genome sequencing data to study population structures and evolution of epidemic, emergent and/or antimicrobial-resistant enteric bacterial pathogens (Njamkepo et al. Nat Microbiol 2016, Weill et al. Science 2017, Tran-Dien et al. Lancet Inf Dis 2018, Hawkey et al. Microb Genom 2019, Weill et al. Nature 2019, Mashe et al. NEJM 2020).

 

Work on this project would include genomic analyses from several hundred genomes using Illumina (isolates) and PacBio/MinION (plasmids) sequences and also microbiological laboratory work such as conjugation assays, omnilog phenotype microarray analyses. The successful candidate will also be responsible for presenting and publishing the study results.

 

Qualified applicant must have a Ph.D. in bioinformatics, microbiology, computer science, or a related field with background and strong interest in microbial evolution. The ideal candidate will already have some experience working with large genomic datasets, experience with basic microbiology techniques and oral and written communication skills as demonstrated by publications as first author in English language peer-reviewed journals and oral presentations at international meetings. Prior programming or scripting expertise is a plus.