Fungal infections can disseminate and become life-threatening if they are not effectively treated. Limited available antifungals combined with drug resistance and drug tolerance can further complicate their treatment. This project seeks to understand how Candida albicans and Cryptococcus neoformans respond and adapt to antifungals, and how extracellular vesicles (EVs) produced by these species impact drug resistance. The project will combine tools in molecular biology, genomics, transcriptomics, and animal models of infection. This project is a collaboration between 3 mycology groups at Institut Pasteur and is funded through the ANR.
The Ene lab is part of the Mycology Department at the Pasteur Institute, Paris, France. Work will be carried out in collaboration with the labs of Guilhem Janbon and Alexandre Alanio, also part of the Mycology Department. The Pasteur Institute an equal opportunity employer and offers a vibrant scientific environment with a particular focus on microbiology and the study of infectious diseases.
Lab website: ene-lab.org and https://research.pasteur.fr/en/team/fungal-heterogeneity/
We seek a highly motivated individual with a Ph.D. degree in microbiology, mycology and/or related fields. The candidate should have significant research experience, a strong publication record, as well as excellent verbal and written communication skills. Knowledge of computer programming (python, R) is advantageous, but not required. Recent PhD graduates with experience in fungal pathogenesis, genetics, drug responses, transcriptomics, and animal models of infection are preferred. The candidate will be encouraged to apply for internal and external funding opportunities. The position is available for 3 years and the candidate will be expected to start as soon as possible.
e-mail firstname.lastname@example.org. Candidates should include a statement of interest and future goals, CV, and 3 reference letters from professionals familiar with their scientific abilities.