Context and environment: The Institut Pasteur is a non-profit private foundation dedicated to fundamental, interdisciplinary research and to translating scientific knowledge to medicine and public health. Topics of research cover microbiology and infectious diseases, cell biology, immunology, developmental biology and stem cells, neuroscience, genomics, genetics and cancer. The Paris campus houses 130 research units belonging to 11 research departments, employing about 2,600 people. It is recognized worldwide as a leader in infectious disease research and is ranked as a top-level institution for publication impact in the field of microbiology and neuroscience.
Host laboratory: The Mass Spectrometry for Biology Lab https://research.pasteur.fr/en/team/mass-spectrometry-for-biology/) headed by Julia Chamot-Rooke is a mixed Institut Pasteur/CNRS Unit. The main research axes of the Unit are: top-down proteomics and structural proteomics (in particular cross-linking mass spectrometry) with major applications in the field of infectious diseases. It is equipped with five Orbitrap mass spectrometers, including Orbitrap Lumos / Eclipse with UVPD and ETD and an Orbitrap HF.
Starting date: ASAP
Job type: Post-doc 24 months minimum
Candidate’s profile: PhD (or post‐doc) in biological mass spectrometry or proteomics. Knowledge in sample preparation, mass spectrometry and in the bioinformatic tools used in proteomics is required. A first practical experience in top-down proteomics and/or Orbitrap MS would be a plus. Good communication, interpersonal skills and experience in presenting concepts and data in oral and written formats (English is necessary).
Gross Salary: 36-43 k€ / year depending on the experience of the candidate and including health insurance and paid annual leave
Project. The objective of the project is to develop new top-down proteomics approaches for the analysis of challenging proteins such as intact antibodies and highly modified proteins important in human health. The developments will be undertaken in the framework of a European project named Topspec (https://topspec.ki.se/) and another project funded by the French Research Agency.
If you are interested, please send a CV and motivation letter to Julia Chamot‐Rooke (firstname.lastname@example.org).