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© Cédric Delevoye
Cellules infectÈes par Chlamydia trachomatis. Les bactÈries se dÈveloppent dans une vacuole (rouge), ‡ proximitÈ du noyau de la cellule-hÙte (bleu). Ce compartiment interagit de faÁon Ètroite avec ceux de la cellule hÙte. Marquage vert= localisation d'une protÈine de l'hÙte, Vamp8, exprimÈe par transfection. Les Chlamydia sont, selon les souches, responsables de maladies sexuellement transmises, de cÈcitÈs, d'infections pulmonaires et pourraient Ítre impliquÈes dans l'athÈrosclÈrose.
Scientific Fields
Diseases
Organisms
Applications
Technique
Application Deadline
31
Dec 2022
2022-12-31 8:00:00 2022-12-31 18:00:00 Europe/Paris CDD Research Engineer CDD Research Engineer Project subject The position stems from a collaboration between three units of the Institut Pasteur (led by C. Buchrieser, M. Hamon, A. Subtil) aiming to identify molecules with antimicrobial properties antimicrobial […] "25-28 rue du Dr. Roux, 75015, Paris" Agathe Subtil agathe.subtil@pasteur.fr

CDD Research Engineer

Project subject

The position stems from a collaboration between three units of the Institut Pasteur (led by C. Buchrieser, M. Hamon, A. Subtil) aiming to identify molecules with antimicrobial properties antimicrobial properties acting at the epigenetic level of the infected host. The person recruited will work in these three units, as well as on the screening platform directed by F. Agou.

Missions :

The engineer will develop the optimal experimental conditions to test the antimicrobial properties antimicrobial properties of small molecules on four pathogens: Chlamydia trachomatis, Legionella pneumophila, Pseudomonas aeruginosas and Streptococcus pneumoniae. Development of the experimental conditions of the screen (reading of the efficacy of the drugs by microscopy and (reading of drug efficacy by microscopy and ELISA test) – Carrying out the 4 screens – Analysis and formatting of the results.

Engineer profile

The candidate will have good experience in cell culture, experience in screening and/or microbiology will be and/or microbiology will be an asset but is not essential. An excellent sense of organisation of work time, and management of generated data (Excel spreadsheet) An ability to adapt to different working environments will be essential.

Starting date : 2023, January 2nd

If you are interesting, please send your CV and a motivation letter to Agathe Subtil : agathe.subtil@pasteur.fr