Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
© Research
Event

Lab Seminar: Layer and Cell Type-Specific Modulation of Neocortical Neuronal Microcircuits

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
19
Nov 2019
Time
11:30:00
25 Rue du Dr Roux, 75015 Paris, France
Address
Building: Fernbach (68)
Location
2019-11-19 11:30:00 2019-11-19 12:30:00 Europe/Paris Lab Seminar: Layer and Cell Type-Specific Modulation of Neocortical Neuronal Microcircuits  The function of neocortical excitatory and inhibitory neurons is under constant control of neuromodulators such as acetylcholine, noradrenaline, dopamine, serotonin and adenosine. Some of these neuromodulatory transmitters (e.g. acetylcholine) can activate ligand-gated ion channels; […] 25 Rue du Dr Roux, 75015 Paris, France Florent Haiss florent.haiss@pasteur.fr

About

 The function of neocortical excitatory and inhibitory neurons is under constant control of neuromodulators such as acetylcholine, noradrenaline, dopamine, serotonin and adenosine. Some of these neuromodulatory transmitters (e.g. acetylcholine) can activate ligand-gated ion channels; however, most act via G-protein coupled receptors which alter the excitability of neurons but also the synaptic release probability. Using patch-clamp recordings and correlated morphological analysis we have studied the effects of several neuromodulators, in particular those of adenosine (a product of ATP degradation) and acetylcholine. We found that their effects are highly cell-specific leading to up- or down-regulation of the excitability of identified neuron types and the synaptic transmission between them. These effects can be exerted at low concentrations and over relatively large distances, thereby altering the cortical-subcortical signal flow.

Contact: Florent Haiss – florent.haiss@pasteur.fr

Location

Building: Fernbach (68)
Address: 25 Rue du Dr Roux, 75015 Paris, France