Department of Microbiology - "Archaeal viruses in natural environments" - Research - Institut Pasteur

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Deputy Director of National Reference Center
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Bisubstrate analogues as N-methyltransferase inhibitors and tool compounds for structural studies – Nathaniel I. Martin Phd

Club viro : 1- Virus d’archaebactéries ; 2- Interférence ARN.

Scientific Fields

Diseases

Organisms

Applications

Technique

Date

13

Apr 2018

Time

11:30:00

28 Rue du Docteur Roux, Paris, France

Address

Building: CFJ

Location

2018-04-13 11:30:00 2018-04-13 12:30:00 Europe/Paris Department of Microbiology – “Archaeal viruses in natural environments” The application of viral and cellular metagenomics to natural environments has expanded our understanding of viral diversity at the population level. Most natural environments are characterized by having a high diversity of microbial and […] 28 Rue du Docteur Roux, Paris, France

Speakers

(Montana State University)

About

The application of viral and cellular metagenomics to natural environments has expanded our understanding of viral diversity at the population level. Most natural environments are characterized by having a high diversity of microbial and viral communities. This diversity makes it difficult to establish a comprehensive understanding of virus-host associations at the single cell level, assign cellular hosts, or determine the extent of viral host range from metagenomics studies alone. Here we combine single-cell sequencing with environmental metagenomics to characterize the structure of virus-host associations in a Yellowstone hot spring microbial community. Leveraging the relatively low diversity of the environment, we are able to overlay evidence at the single-cell level with contextualized viral and cellular community structure. The new lens provided by the combination of metaviromics and single-cell genomics exposes the impact of viruses in extreme environments, supports the possibility that extensive host-virus associations are a common feature of many environments, and further expands the unseen impact of viruses.

Location

Building: CFJ
Address: 28 Rue du Docteur Roux, Paris, France

Published on: 03 Apr 2018 • Modified on: 23 Aug 2018

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