About

Founded in September 2014, the Center for Global Health (CGH) works to improve health conditions of populations worldwide through three main pillars of intervention: Research, Outbreak Investigation, Education and Training. 

CGH’s missions:

  • Promote a global health scientific strategy using state-of-the-art technology to address the most significant public health challenges worldwide
  • Educate and equip the next generation of global health scientists and practitioners
  • Support local authorities in the management of and response to infectious disease outbreaks, to better understand emergence and transmission patterns in order to limit further spread in human populations.
  • Increase awareness of the great breadth of global health research and activities conducted at Institut Pasteur and the International Network of Institut Pasteur (IPIN)

 

Outbreak Investigation Taskforce

(EN)

Institut Pasteur’s Response to Emerging and Re-emerging Infectious Disease Outbreaks
The Institut Pasteur International Network has a long tradition in working closely with local ministries of health on training and building capacity to detect and respond to outbreaks of known and unknown pathogens. Since 2014, Institut Pasteur has formalized its process for responding to infectious disease outbreaks with the inception of the Outbreak Investigation Task Force (OITF).
  • What is the Outbreak Investigation Task Force?

The Outbreak Investigation Task Force consists of Pasteurians with experience in field investigations of infectious diseases and with expertise in epidemiology, clinical infectious diseases, virology, bacteriology, entomology, logistics, risk communication and other fields. OITF members receive advanced training in field-based teamwork, coordination with local governments and partner organizations, epidemiologic investigations, adaption of studies to field interventions, database use and management, and report writing. OITF task force members are then, upon request, able to be deployed rapidly to support an outbreak of emerging and re-emerging pathogens.

  • How does the OITF operate?

The primary aim of the OITF is to support local authorities in the management of and response to an infectious disease outbreak. Upon notification of a novel or re-emerging pathogen, and at the request of local authorities, the OITF can rapidly deploy staff during the early stages of an outbreak. We will work in support of the local Instituts Pasteur, in partnership with World Health Organization’s Global Outbreak Alert and Response Network (GOARN), and/or through bi-lateral agreements with national governments. Working with local partners, our rapid-response teams investigate pathogen transmission, identify the populations most at risk for infection and severe outcomes and develop mitigation measures to control the spread of the disease. 

We rapidly implement epidemiologic studies and utilize our expertise in mathematical modelling and genetic sequencing to inform policy decisions to reduce the impact of the outbreak. Data gathered at the outbreak’s onset will be used for the development of diagnostic tools and medical interventions, including vaccines

  • A mechanism for advancing the One Health initiative

Human health, animal health and the state of ecosystems are inextricably linked with approximately 75% of emerging and re-emerging infectious diseases that have affected humans over the past three decades are known to be of zoonotic origin. In recognition of the fact that global surveillance of infectious diseases must therefore expand beyond humans to include animal and environmental aspects of pathogen emergence and re-emergence, the Institut Pasteur, through the CGH and the OITF, has become a key proponent of the ‘One Health’ initiative. The Institut Pasteur and the IPIN regularly conducts and coordinates multi-sectorial investigations of human cases of diseases from rabies to H5N1 in collaboration with the Ministries of Agriculture and the Ministries of Health in affected countries, placing the Institut Pasteur and the OITF in a position to advance the ‘One Health’ initiative on the global health agenda.

  • Contacts

Education and Training

Recent outbreaks have underscored the need for rapid and professional interventions grounded in expertise in both basic and applied biosciences
Building on the wide spectrum of educational opportunities offered by the Institut Pasteur and the IPIN, the CGH develops new courses that combine a global health dimension with multidisciplinary courses and practical experience. The CGH also actively forges partnerships to make basic and advanced courses more accessible to students across the globe.
  • Innovative online learning

In order to provide flexible and rapid access to training, the CGH collaborates in the development of online learning tools and resources at the Institut Pasteur. This facilitates the continuing scientific education and training of students, scientists, and public health professionals across disciplines and geographic locations. In response to the success of the first Pasteur/Cnam Massive Open Online Course (MOOC) entitled “Concepts and Methods in Epidemiology”, the CGH is producing additional online courses in vaccinology, neurology, entomology, immunology, and stem cell biology and regenerative medicine. Moreover, the CGH and the IPIN are developing a specialized e-learning platform. This platform shall offer basic science and practical courses specifically related to global health.

  • Developing a bespoke Pan-African capacity strengthening program

The Center for Global Health and the IPIN are currently working on developing a bespoke Pan-African capacity strengthening program with the goal to support health research and training in Africa. In addition to building local expertise, it will aim to strengthen the Pan-African research collaboration by linking research groups across the continent, especially between the Francophone and Anglophone regions.

The aim is to offer a bespoke, demand – led support platform, based on the existing research strengths, current and future research ambitions, as well as identified skill gaps at Institutions of Higher Education across Africa, developed in collaboration with relevant stakeholders on the continent and beyond.

The program will focus on the next generation of researches, particularly post-graduates and post-docs, and their career development and employability. Furthermore, it will aspire to better integrate researchers into the existing health research networks in Africa.

The capacity strengthening program will concentrate on two research priority areas: emerging infectious diseases and antimicrobial resistance (AMR), with Malaria being the third possible area of research. Training opportunities within these priority domains include bioinformatics and biostatistics, molecular genetics (including human genetics), training on –omics technology, but also lab training in areas such as microbiology.