About

An international reference center for processing, analyzing and modeling biology data.

We live at a time when biology is producing vast reams of data, and mathematical modeling, statistics and computing are increasingly vital to help us understand them. The Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI), set up in March 2015, is a multidisciplinary, transversal structure for large-scale data processing at the Institut Pasteur.

The C3BI facilitates cooperation and dialog on bioinformatics issues at the Institut Pasteur. It develops methodological research in computer science and statistics, offers support to experimental research units and works in conjunction with the Institut Pasteur International Network. The International Group for Data Analysis is responsible for developing bioinformatics activities and training in this field within the International Network.

A research area

The C3BI is composed of teams of scientists who work closely with the Institut Pasteur’s departments in highly varied research fields:

The C3BI is coordinating a highly ambitious research project: INCEPTION, which stands for INstitut Convergence: Emergence of Pathology Through Individuals and PopulatiONs. This project, selected for funding in 2016 by the , aims to improve understanding and monitoring of the emergence of diseases in populations (epidemic control, etc.) and individuals (precision medicine, etc.). In the INCEPTION framework, the C3BI applies new bioinformatics and biostatistics methods to help scientists understand and make use of the profusion of biological data generated by experimental biology, public health and clinical research.

A bioinformatics platform

“I need you to analyze the data that we’ve collected.” The C3BI responds to requests like this from teams at the Institut Pasteur and within its International Network. It analyzes data via its bioinformatics platform, which meets wide-ranging needs in this field. The recruitment of around thirty scientists and engineers from 2014 to 2016 will enable the C3BI to perform large-scale data analysis. In 2018, a new building with space for 120 people will bring all the C3BI teams together under the same roof on the Paris campus.

The Institut Pasteur’s bioinformatics platform is a reference center and a member of the ELIXIR European network and the French Institute of Bioinformatics.

Training opportunities

The C3BI offers a wide variety of training opportunities for biologists, mathematicians, computer scientists, statisticians and other professionals, either as part of PhD training programs or for working scientists. For example, training courses on high-throughput sequencing data analysis have been held at institutes in the Institut Pasteur International Network (in Montevideo, Dakar and São Paulo) and on the Paris campus.

 

Find out more about the Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI) https://c3bi.pasteur.fr

“Until the late 1990s, biology was a discipline that was carried out using test tubes and Petri dishes. Nowadays, biologists are just as likely to be sat at a computer as they are working in a lab. And that applies to all areas of biology. The Institut Pasteur is approaching this new field with a great deal of energy and commitment.”

Olivier Gascuel, Director of the Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI)

News

Events

Ecole thématique – Bioinformatics of protein­-protein interactions for wet lab scientists

The course is intended for PhD students and postdocs working in experimental biology, but scientist of all levels are welcome. Participants will be introduced to a wide variety of popular bioinformatic tools aimed at […]

2017-04-03 09:00:00 2017-04-07 18:00:00 Europe/London Ecole thématique – Bioinformatics of protein­-protein interactions for wet lab scientists The course is intended for PhD students and postdocs working in experimental biology, but scientist of all levels are welcome. Participants will be introduced to a wide variety of popular bioinformatic tools aimed at […] 25 Rue du Docteur Roux, Paris, France

« Joint analysis of multiple phenotypes using GWAS summary statistics» by Hugues ASCHARD

Hugues Aschard P.I.  G5 Génétique Statistique « InBio » (C3BI) Institut Pasteur Genome-wide association studies (GWAS) have proven successful in identifying thousands of significant genetic associations for multiple traits and diseases. This success is largely thanks […]

2017-05-11 11:00:00 2017-05-11 00:30:00 Europe/London « Joint analysis of multiple phenotypes using GWAS summary statistics» by Hugues ASCHARD Hugues Aschard P.I.  G5 Génétique Statistique « InBio » (C3BI) Institut Pasteur Genome-wide association studies (GWAS) have proven successful in identifying thousands of significant genetic associations for multiple traits and diseases. This success is largely thanks […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Pathogen dynamics through a phylogenetic lens – zooming into the spread of Ebola, Diphtheria, Tuberculosis, Influenza and HIV

Tanja Stadler will talk about Pathogen dynamics through a phylogenetic lens – zooming into the spread of Ebola, Diphtheria, Tuberculosis, Influenza and HIV Pathogen dynamics through a phylogenetic lens – zooming into the spread […]

2017-05-18 14:00:00 2017-05-18 Europe/London Pathogen dynamics through a phylogenetic lens – zooming into the spread of Ebola, Diphtheria, Tuberculosis, Influenza and HIV Tanja Stadler will talk about Pathogen dynamics through a phylogenetic lens – zooming into the spread of Ebola, Diphtheria, Tuberculosis, Influenza and HIV Pathogen dynamics through a phylogenetic lens – zooming into the spread […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Genetic basis of gene regulation: genome-wide models and applications to diagnosis

Julien Gagneur will talk about Genetic basis of gene regulation: genome-wide models and applications to diagnosis. Genetic basis of gene regulation: genome-wide models and applications to diagnosis Registration Apply here

2017-06-01 14:00:00 2017-06-01 Europe/London Genetic basis of gene regulation: genome-wide models and applications to diagnosis Julien Gagneur will talk about Genetic basis of gene regulation: genome-wide models and applications to diagnosis. Genetic basis of gene regulation: genome-wide models and applications to diagnosis Registration Apply here Institut Pasteur, Rue du Docteur Roux, Paris, France

Between chaos and determinism: the evolution of stochastic gene expression

Julien Dutheil will talk about Between chaos and determinism: the evolution of stochastic gene expression While often depicted as finely tuned programs, biochemical processes in the cell are subject to random fluctuations because of […]

2017-06-15 14:00:00 2017-06-15 16:00:00 Europe/London Between chaos and determinism: the evolution of stochastic gene expression Julien Dutheil will talk about Between chaos and determinism: the evolution of stochastic gene expression While often depicted as finely tuned programs, biochemical processes in the cell are subject to random fluctuations because of […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Teams

Jobs